ABOUT ME
-
Position: Full Professor in the Chemistry department, Bar-Ilan University.
-
Professional experience: Leading a research group focusing on drug development and diagnostics, involved in national and international collaborations both in academia and industry for the last 23 years.
-
Over 130 papers and 9 patents.
-
Selected appointments: Dean of Exact Sciences Faculty, Vice Dean of Graduate School, former Head of Department of Chemistry, Bar-Ilan senate member, Rector’s advisor for promotion of women in academia, Member of the University Appointment and Promotion Committee, Member of prize and fellowship committees, such as the Israel Prize in Chemistry and Physics, Fulbright Foundation, etc.
-
Prizes: Teva Prize for excellent young scientists; Juludan Prize for the Application of Exact Sciences to Medicine; Shoham Prize for arts
EDUCATION
RESEARCH INTERESTS
1991-1993
National Institutes of Health (NIH)
Post-doctorate (chemistry of nucleosides and nucleotides, molecular modeling) under the supervision of Dr. K. Jacobson.
1984-1990
Bar-Ilan University
PhD in Organic Chemistry (chemistry of heterocycles) under the supervision of Prof. A. Hassner.
1982-1983
Bar-Ilan University
MSc degree in Medicinal Chemistry (chemistry of carbohydrates) under the supervision of Prof. A. Nudelman.
Medicinal Chemistry
development of drugs for the treatment of - type II diabetes, glaucoma, Alzheimer’s disease, osteoarthritis, and inflammatory bowel diseases.
Diagnostics
development of fluorescent probes for diagnostics of breast cancer.
The chemistry and biochemistry of nucleosides/nucleotides and nucleic acids
development of synthetic methodologies; development of novel building blocks and novel bioisosteres; conformational analysis; determination of acidity constants and stability constants of nucleotide complexes with metal-ions; purinergic receptors; nucleotide metabolizing enzymes.